Zea Mays cobs were fermented with S. cerevisiae to determine its effect on the protein level of these starchy waste. Chemical analysis of fermented substrates showed substantial increase in crude protein (10.37%) after 7 days, and corresponding decrease in toxic components (oxalic acid, tannins, phytic acid, and hydrocyanic acid). At optimum pH 5.0, temperature of 28 C and moisture level of 130%, there were increases in level of crude protein. Supplementation of the substrates with inorganic nitrogen sources supported high protein and low toxic levels with urea giving the best results. The possibility of using fermented corn cobs in livestock feeds and thereby changing corn cobs from menace status to profitability status is highlighted.