The research examined the influence of indigenous knowledge management on the food security of Ghanaian subsistence yam farmers amid the COVID-19 pandemic, utilising a descriptive correlation survey approach. The study encompassed 384 yam farmers selected using a multistage sampling procedure. Descriptive and inferential statistics were employed in the study. A statistically significant relationship was found between food security and various elements that support knowledge management processes. These factors, along with knowledge distribution (i.e. dissemination of indigenous knowledge) and knowledge conversion (i.e. adapting indigenous knowledge into community activities), jointly explained 74.0% of food
security variation among peasant farmers during the pandemic. Indigenous knowledge management positively impacted food security in this context. Integrating indigenous knowledge with modern agricultural practices could enhance productivity and sustainability. The study underscores the importance of involving local communities in designing food security interventions for lasting positive impacts on livelihoods. It recommends the active participation of local people in shaping such interventions.