The chemical composition of Cola nitida and Cola rostada pods and seeds showed average moisture content of 81.75% whereas the seeds had an average of 54.60%. Crude protein ranged from 9.60-11.91% for the pods and 10.50-11-91% for the seeds. Lipid for both was less than 2%. Fibre of the pod was 15% while that of the seed ranged from 2% to 3.6%. The toxicant levels were generally low. The plants parts had low concentration of heavy metals such as cobalt, cadmium, and lead. The phytochemical components included alkaloids, saponins, tannins, polyphenols, and reducing compounds. The extracts inhibited Escherichia coli, Staphylococcus aureus, β-haemolytic Streptococcus and Klebsiella pneumonia. There is an urgent need to establish the main bioactive agent and to experiment the use of the parts livestock feed.